Uncaria tomentosa (Willd.) DC (vilcacora) – chemizm i właściwości biologiczne

1. Heitzmann ME, Neto CC, Winiarz E et al. Ethnobotany, phytochemistry and pharmacology of Uncaria ( Rubiaceae); Phytochem 2005 66:5-29. 2. Keplinger K, Laus G, Wurm M i wsp. Uncaria tomentosa (Willd.) DC. – Ethnomedicinal use and new pharmacological, toxicological and botanical results. J Ethnopharmacol 1999; 64:23-34. 3. Obregon LE: Cat´s claw, Uncaria genus. Botanical, chemical and pharmacological studies of Uncaria tomentosa (Willd.) DC ( Rubiaceae) and Uncaria gujanensis (Aubl.) Gmel. Lima, Peru: Instituto de Fitoterapia Americano; 1995. 4. Pilarski R, Zieliński H, Ciesiołka D, Gulewicz K: Antioxidant activity of ethanolic and aqueous extracts of Uncaria tomentosa (Willd.) DC; J Ethnopharmacol 2006; 104:18-23. 5. Steinberg PN: Cat´s claw; an herb from the Peruvian Amazon. Sidahora 1995; 35-6. 6. Cerri R, Aquino R, De Simone F, Pizza C: New quinonic acid glycoside from Uncaria tomentosa. J Nat Prod 1988 51(2):257-61. 7. Piscoya J, Rodriguez Z, Bustamante SA et al. Efficacy and safety of freeze-dried cat´s claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria gujanensis. Inflammation Res 2001; 50:442-48. 8. Wagner H, Kreutzkamp B, Jurcic K. Alkaloids of Uncaria tomentosa and their fagocytosis enhancement activity. Planta Med 1985; 51:419-23. 9. Gattuso M, Di Sapio O, Gattuso S, Pereyra EL: Morphoanatomical studies of Uncaria tomentosa and Uncaria gujanensis bark and leaves. Phytomed 2004; 11:213-23. 10. Laus G, Brőssner D, Keplinger K. Alkaloids of Peruvian Uncaria tomentosa. Phytochem 1997; 45:855-60. 11. Lemaire I, Assineve V. Cano P et al. Stimulation of interleukin-1 and –6 production in alveolar macrophages by the neotropical liana, Uncaria tomentosa (Una de Gato); J Ethnopharmacol 1999; 64:109-15. 12. Senatore A, Cataldo A, Jaccarino FP. Phytochemical and biological study of Uncaria tomentosa Bolletino della Societa Italiana di Biologia Sperimentale 1989; 65:517-20. 13. Aquino R, De Feo V, De Simone F et al. New compounds and antiinflammatory activity of Uncaria tomentosa. J Nat Prod 1991; 54:453-9. 14. Aquino R, De Tommasi N, De Simone F, Pizza C: Triterpenes and quinonic acid glycosides from Uncaria tomentosa; Phyochem 1997; 45(5):1035-40. 15. Sandoval M, Okuhama NN, Zhang XJ i wsp. Anti-inflammatory and antioxidant activities of cat´s claw ( Uncaria tomentosa and Uncaria gujanensis) are independent of their alkaloid content. Phytomed 2002; 9:325-37. 16. Sheng Y, Akesson C, Holmgren K et al. An active ingredient of cat´s claw water extracts. Identification and efficacy of quinic acid. J Ethnopharmacol 2005; 96:577-84. 17. Desmarchelier C, Mongelli E, Coussio J, Ciccia G: Evaluation of the in vitro antioxidant activity in extracts of Uncaria tomentosa (Willd.) DC; Phytother Res 1997; 11:254-6. 18. Jürgensen S, Dalbó S, Angers P et al. Involvement of 5-HT₂ receptors in the antinociceptive effect of Uncaria tomentosa; Pharmacol, Biochem and Behavior 2005; 81:466-77. 19. Sandoval M, Charbonnet RM, Okuhama NN i wsp. Cat´s claw inhibits TNF-alpha production and scavenges free radicals: role in cytoprotection. Free Rad Biol Med 2000; 29:7178. 20. Sheng Y, Pero RW, Amiri A i wsp. Induction of apoptosis and inhibition of proliferation in human tumor cells treated with extracts of Uncaria tomentosa; Anticancer Res 1998 18(5A):3363-8. 21. Sroka Z, Fecka I, Cisowski W, Łuczkiewicz M: Investigation into the anti-radical activity of extracts obtained from Uncaria tomentosa (Willd.) DC; Herba Pol 2001; 47:218-23. 22. Riva L, Coradini D, Di Fronzo G et al. The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line; Anticancer Res 2001; 21:2457-62. 23. Wirth C, Wagner H. Pharmacologically active procyanidins from the bark of Uncaria tomentosa; Phytomed 1997; 4(3):265-6. 24. Reinhard KH: Uncaria tomentosa (Willd.)DC: cat´s claw una de gato, or saventaro. J Altern Compl Med 1999 5:143-51. 25. Wurm M, Kacani L, Laus G, et al. Pentacyclic oxindole alkaloids from Uncaria tomentosa induce human endothelial cells to release a lymphocyte proliferation- regulating factor. Planta Med 1998; 64:701-4. 26. Rizzi R, Re F, Bianchi RF et al. Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts. J Ethnopharmacol 1993; 38:63-77. 27. Santa Maria A, Lopez A, Diaz MM et al. Evaluation of the toxicity of Uncaria tomentosa by bioassays in vitro. J Ethnopharmacol 1997; 57:183-7. 28. Sandoval-Chacon M, Thompson JH, Zhang XJ et al. Antiinflammatory action of cat´s claw: the role of NF-kappaB. Alimentary Pharmacol Therap 1998; 12:1279-89. 29. Sandoval M, Mannick EE, Mishra J et al. Cat´s claw ( Uncaria tomentosa) protects against oxidative stress and indomethacin-induced intestinal inflammation. Gastroenterology 1997; 112 suppl: A 1081. 30. Hardin SR: Cat´s claw: An Amazonian vine decreases inflammation in osteoarthritis; Complement. Ther Clin Practice 2007; 13:25-28. 31. Akesson Ch, Pero RW, Ivars F. C-Med 100, a hot water extract of Uncaria tomentosa, prolongs lymphocyte survival in vivo; Phytomed 2003; 10:23-33. 32. Mammone T, Akesson C, Gan D et al. A water soluble extract from Uncaria tomentosa (cat´s claw) is a potent enhancer of DNA repair in primary organ cultures of human skin; Phytother Res 2006; 20:178-83. 33. Cisneros FJ. Jayo M, Niedziela L. An Uncaria tomentosa (cat´s claw) extract protects mice against ozone-induced lung inflammation. J Ethnopharmacol 2005; 96:355-64. 34. Eberlin S, Dos Santos LMB, Queiroz MLS: Uncaria tomentosa extract increases the number of myeloid progenitor cells in the bone marrow of mice infected with Listeria monocytogenes; Intern Immunopharmacol 2005; 5:1235-46. 35. Allen-Hall L, Cano P, Arnason JT i wsp. Treatment of THP-1 cells with Uncaria tomentosa extracts differentially regulates the expression of IL-1β and TNF-α; J Ethnopharmacol 2007; 109:312-17. 36. Cheng AC, Jian CB, Huang YT. Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells. Food Chem Toxicol 2007; 45: 2206-18.