current
issue
2/2013

Niedożywienie białkowo-kaloryczne w zaawansowanych stadiach przewlekłych chorób wątroby

© Borgis - Medycyna Rodzinna 1, p. 11-14
*Barbara Rejman-Gruszka1, Krzysztof Simon2
Niedożywienie białkowo-kaloryczne w zaawansowanych stadiach przewlekłych chorób wątroby
PROTEIN – ENERGY MALNUTRITION IN END-STAGE CHRONIC LIVER DISEASES
1VI Oddział Wewnętrzny Wojewódzkiego Szpitala Specjalistycznego im. J. Gromkowskiego we Wrocławiu
Ordynator Oddziału: dr n. med Krzysztof Krause
2Katedra i Klinika Chorób Zakaźnych, Wątroby i Nabytych Niedoborów Odpornościowych Akademii Medycznej we Wrocławiu
Kierownik Kliniki: prof. dr hab. Andrzej Gładysz
Summary
Chronic liver diseases predispose to protein-energy malnutrition. The etiology of malnutrition in those illnesses is multifactorial and take into consideration anorexia and digestion disorders, malapsorption and increased energy expenditure. The poor nutritional status causes an aggravated risk of complications and deteriorates prognoses of patients with chronic liver diseases. Therefore early identyfication of undernourished patients becomes very significant for early begining of clinical nutrition, what will prevent or delay appearance of complications, particularly ascites, gastrointestinal varices bleeding or encephalopathy. The assessment of nutritional status is mainly based on Subjective Global Assessment SGA, also contains details from anamnesis and physical examination with anthropometric and clinical measurements. Malnourished patients in end-stage liver diseases reveal increased protein and energy intake, but improvement of their nutritional status depends on proper glycemia regulation, vitamins and micronutrients suplementation. Generally an oral nutritional supplements are recommended. An enteral nutrition is restricted for selected clinical situations and ussually takes a place by the nasogastric tube, while total parenteral nutrition is administered only to maintain appropriate nutritional status of patients after liver transplantation. There is no restrictions in dietary protein intake nowadays. It should be consumed 4-6 smaller and more frequent meals, with nocturnal carbohydrated snack. This article reviews problems of malnutrition in end-stage liver diseases.
Key words: end-stage liver diseases, malnutrition, nutritional support
Piśmiennictwo
1. Pertkiewicz M: Niedożywienie i jego następstwa. Postępy Żywienia Klinicznego Nr 2/2008; (8)3: 4-8. 2. Kunecki M: Leczenie żywieniowe w chorobach wątroby. Postępy Żywienia Klinicznego Nr 2/2008 (8)3: 42-44. 3. Boroń -Kaczmarska A: Żywienie w chorobach wątroby www.mp.pl/artykuły. 4. Henkel AS, Buchman AL: Nutritional support in patients with chronic liver disease, Nature Clinical Practice Gastroenterology&Hepatology 2006; 3, 4: 202-20-9. 5. Sanchez AJ, Aranda-Michel J: Nutrition for the Liver transplant Patients. Liver Transpl 2006; 12: 1310-1316. 6. Zein NN et al.: Prevalence of diabetes mellitus in patients with end-stage liver cirrhosis due to hepatitis C, alcohol,or cholestatic disease. J Hepatol 2000; 32: 209-217. 7. Mueller MJ: Malnutrition and hypermetabolism in patients with liver cirrhosis. Am J Clin Nutr 2007; 85: 1167-8. 8. Albertino F: Nutrition and survival in patients with liver cirrhosis. Nutrition 2001; 17: 445-450. 9. Roongpisuthipong C et al.: Nutritional Assessment in Various Stages of Liver Cirrhosis. Nutrition 2001; 17: 761-765. 10. Merli M, Reggio O, Dally L and PINC: Does Malnutrition Affect Survival in Cirrhosis? Am J Clin Nutr 2007; 85: 1167-8. 11. Szczygieł B: Ocena stanu odżywienia. Stan odżywienia Prof. Szczygieł.pdf 12. Zmarzły A: Niedożywienie. [W:] Steciwko A: Wybrane zagadnienia z praktyki lekarza rodzinnego, t. 11, Wydawnictwo Continuo Wrocław 2007; p. 26-43. 13. Campillo B, Richardet J-P, Bories PN: Enteral nutrition in severely malnourished and anorectic cirrhotic patients in clinical practice. Gastroenterol Clin Biol 2005; 29: 645-651. 14. Plauth M: Żywienie enteralne w chorobach wątroby. Wytyczne European Society for Clinical Nutrition and Metabolism, ESPEN guideliness on enteral nutrition: liver disease. Clinical Nutrition 2006; 25: 285-294. 15. Kościuk N: Wpływ niedożywienia na parametry laboratoryjne. In Vitro Explorer 2007; 1(6): 23-28. 16. Schulz GJ, Campos AC, Coehlo JC: The role of nutrition in hepatic encephalopathy. Curr Opin Clin Nutr Metab Care 2008; 11(3): 275-80. 17. Mesejo A, Juan M, Serrano A: Liver cirrhosis and encephalopathy: clinical and metabolic consequences and nutritional support. Nutr Hosp 2008; 23 Suppl 2: 8-18. 18. Stickel F, Inderbitzin D, Candinas D: Role of nutrition in liver transplantation for end-stage chronic liver disease. Nutr Rev 2008; 66(1): 47-54. 19. Caly WR, Strauss E, Carrilho FJ and Laudann AA: Different degrees of malnutrition and immunological alterations according to aetiology of cirrosis: a prospective and sequential study. Nutrition Journal 2003; 2: 10. 20. Cordoba J et al.: Normal protein diet for episodic hepatic encephalopathy: results of a randomized study. J Hepatol 2004; 41(1): 147-8.

otrzymano/received: 2008-11-11
zaakceptowano/accepted: 2009-01-05

Adres/address:
*Barbara Rejman-Gruszka
VI Oddział Wewnętrzny,
Wojewódzki Szpital Specjalistyczny im. J. Gromkowskiego
ul. Koszarowa 5, 51-149 Wrocław
tel.: (0-71) 325 03 56
e-mail: brejman@wp.pl

The whole paper PROTEIN – ENERGY MALNUTRITION IN END-STAGE CHRONIC LIVER DISEASES is also available at On-line Medical Library.
Copyright © Borgis Medical Publisher Ltd. 2007-2011